Described as “deliberately challenging”, the new time-to-treatment targets published by the Vascular Society of Great Britain and Ireland (VSGBI), as part of the Peripheral Arterial Disease Quality Improvement Framework, have prompted a number of different measures in the UK...
LimFlow, a specialist in minimally-invasive technology for the treatment of chronic limb-threatening ischemia (CLTI), a severe form of peripheral artery disease (PAD), has announced that the first patient has been treated in its PROMISE II US pivotal trial of...
A new initiative supported by both the Association for the Advancement of Wound Care (AAWC) and the Wound Healing Society (WHS)—the “Wound Care Expert/FDA-Clinical Endpoint Project” (WEF-CEP)—will take an updated list of primary endpoints for wound care trials to...
Inpatient wound services are an essential component of care that can improve the likelihood of patients returning as outpatients, thereby reducing readmissions, Christi Cavaliere (Cleveland Clinic, Cleveland, USA) told the annual meeting of the American College of Wound Healing...
There is no significant benefit to the use of nanocrystalline-coated silver dressings over standard wound dressings, following coronary revascularisation, in patients with type 2 diabetes, according to the results of a study conducted with 194 patients. Results of the...
Using an implant containing gentamicin in the groin area following vascular surgery does not significantly reduce the incidence of infected wounds during the postoperative course, according to a new study presented at the European Society for Vascular Surgery annual...
MolecuLight, a specialist in handheld fluorescence imaging for real-time visualisation of fluorescence in wounds, has received FDA 510(k) clearance for its i:X handheld fluorescence imaging device for use in the detection of wounds containing bacteria. This FDA 510(k) clearance...
Orpyx has announced the launch of its Orpyx SI Sensory Insoles with remote patient monitoring for the prevention of diabetic foot ulcers (DFU) and neuropathy-related ulcers. By monitoring pressure, temperature, and movement, the Orpyx SI Sensory Insole system provides the wearer with...
In the UK, the lower limb amputation rate has not improved significantly since 2012, and is contributed to heavily by the high incidence of infection and ischaemia in patients with diabetic wounds. Michael Edmonds (King’s College Hospital , London,...
With the rising importance of high-quality research in the field of wound care and healing, there is a need for key players from all disciplines across the wound care spectrum to collaborate. Writing for iWounds News, editorial board member...
Wound care specialists can improve microcirculation by maximising “the overall vascular health of patients” It is the refrain William Ennis (University of Illinois, Chicago, USA) hears continually: “I cannot do anything about the microcirculation!” His swift response however, at...
Implementation of an evidence-based pathway for leg ulcer care in community nursing has resulted in a significant reduction in healing times, according to research conducted by the Manchester University NHS Foundation Trust, Manchester, UK. Although quality of life scores...
Initial findings of an early feasibility trial have demonstrated that the LimFlow System does represent a safe and reproducible method of treating patients with no-option critical limb ischaemia (CLI). The results of PROMISE I, which were described by chief...
As part of newly published international guidelines on the prevention and treatment of pressure ulcers, it has been revealed that these wounds occur, primarily, due to the deformation and distortion of cells and tissues. Previously, it was understood that...
The 2019 Prevention and Treatment of Pressure Ulcers/Injuries: Clinical Practice Guideline, published on 15 November 2019, has introduced new evidence-based recommendations for using a "subepidermal moisture (SEM)/oedema measurement device as an adjunct to routine clinical assessment." "The days of subjective...
“Our aim is to establish the underlying economic and clinical case for change, identify what needs to happen and describe how we make that change happen” argued Una Adderley, director of the National Wound Care Strategy Programme, who was...
US wound care service providers operating in skilled nursing facilities were urged to follow a new set of steps when attending to patients amid a new billing system adopted by the Centers for Medicare and Medicaid Services (CMS), according...
The National Pressure Ulcer Advisory Panel (NPUAP) has announced that it has changed its name to the National Pressure Injury Advisory Panel (NPIAP). According to a statement, the new name reflects the future direction of the organisation and reaffirms...
William ennis illustration

William Ennis

William Ennis is currently Catherine and Francis Burzik professor of Wound Healing and Tissue Repair, and chief of Wound Healing Section, University of Illinois, Chicago, USA. With his 25 years of experience practising wound care, Ennis speaks about what...
The efficacy of the Kerecis fish skin treatment for diabetic lower-extremity wounds has been affirmed in a new peer-reviewed article published in the journal Wounds.  The paper, “Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: a Retrospective Study...
Imbed Biosciences, a biotech company which specialises in the development of advanced therapies for burns, chronic ulcers and surgical wounds, has announced that it has closed its Series A Preferred Stock equity financing, which was expanded to US$4 million...
MolecuLight Inc, a provider of handheld fluorescence imaging for real-time visualisation of bacteria for chronic wounds, has been informed by the American Medical Association (AMA) that in its summary of panel actions September 2019 meeting, the CPT Editorial Panel...
Following their publication in the American Diabetes Association (ADA) journal Diabetes Care, results of a double-blinded, randomised controlled trial have been announced, showing that at both 12 weeks and 12 months, adjunctive cyclical pressurised topical oxygen wound therapy (TWO2)...
The superiority of fish-skin xenografts over dehydrated human amnion/chorion allografts (dHACM) for the treatment of acute wounds has been established in a randomised controlled trial published in Wound Repair Regeneration. Conducted by Robert Kirsner (University of Miami Miller School...
Masters Speciality Pharma, a UK-headquartered pharmaceutical company "specialising in the global distribution of high-quality, life-changing medicines", has announced the launch of Neuropad, a rapid and reliable screening test for diabetic foot syndrome, in Brazil. According to a statement, diabetes is...
Improvements that enable better miniaturisation of technology leads to higher-quality wearable health solutions, including digital devices that were “never before possible’, said Breanne Everett (Orpyx Medical Technologies, Calgary, Canada) at the American College of Wound Healing and Tissue Repair...
Microbion Corporation has announced results from a Phase 1b trial of its microbial bioenergetic inhibitor, pravibismane, in patients with moderate to severe infected diabetic foot ulcers (DFUs). The findings of the trial were presented at the Symposium on Advanced Wound Care...
It has been found that the application of dehydrated human amnion and chorion allografts (dHACA) results in a better venous leg ulcer (VLU) healing rate than the use of standard multilayer compression therapy, following a randomised controlled study comparing...
There is a growing need for wound care amid higher rates of chronic wounds—somewhere in the vicinity of five to seven million in the United States per year—at a cost level in excess of US$25 billion, Venita Chandra (Stanford...
A report titled ‘Venous Leg Ulcers: A Silent Crisis’ has been published by the All-Party Parliamentary Group on Vascular and Venous Disease (VVAPPG) at an event held at the Palace of Westminster, highlighting the opportunities available to help thousands...
Based on the results of the INVIPS trial, incisional negative pressure wound therapy (INPWT) has been shown to decrease the risk of surgical site infections (SSIs) following vascular surgery with inguinal incision. Conducted at Skane University Hospital (Malmӧ, Sweden),...
WoundVision, the manufacturer of the industry's first long-wave infrared thermography (LWIT) solution for mitigating risk associated with hospital-acquired pressure injuries (HAPIs) and other wounds, has announced the expansion of its product offering with the debut of the Scout Mobile...
In this issue of iWounds News: Clinical trials confirm efficacy of TLC-NOSF dressing IWGDF unveils new infection and PAD guidelines Michael Edmonds: A new dawn in diabetic foot care Karen Imma Gellada: Wound care specialisation Profile: William Ennis
In this issue of iWounds News: Clinical trials confirm efficacy of TLC-NOSF dressing IWGDF unveils new infection and PAD guidelines Michael Edmonds: A new dawn in diabetic foot care Karen Imma Gellada: Wound care specialisation Profile: William Ennis
LifeNet Health's Dermacell AWM, an advanced acellular dermal matrix (ADM) for wound treatment, is the first human ADM available in India. According to a statement, this introduction will provide access to proven therapy for millions of patients in India suffering...
PolarityTE, a company specialised in regenerative tissue products and biomaterials, has announced findings from an open-label, single-arm pilot study, which examined the impact of SkinTE in closing venous stasis leg ulcers (VLUs) following the failure of conventional treatments. The clinical outcomes...
Advanced fluorescence imaging has the potential to decrease bioburden and significantly improve the healing rates of chronic wounds, according to the results of a case series investigation conducted in Cleveland, USA. As well as targeting debridement to promote wound...
A pilot evaluation of a new multilayer wound dressing has confirmed its efficacy for transporting exudate containing toxic matrix metalloproteases (MMPs) away from chronic venous leg ulcers (VLUs). Conducted by Oscar M Alvarez (University Hospital; Rutgers New Jersey Medical...
Turn Therapeutics, a Los Angeles-based pharmaceutical and medical device company, has announced that it has received FDA clearance for its Protego antimicrobial wound dressing, which is described as a disruptive innovation to traditional petroleum saturated gauze dressings. Protego wound...
3M has announced that it has completed the acquisition of Acelity and its KCI subsidiaries from a consortium comprised of funds advised by Apax Partners (the Apax Funds), together with controlled affiliates of the Canada Pension Plan Investment Board...
Source: CRF At the 2019 Transcatheter Cardiovascular Therapeutics (TCT) meeting (25–29 September, San Francisco, USA), InterVene won the TCT-Shark Tank Innovation Competition for its novel endovenous system (BlueLeaf) for forming valves in patients with deep vein reflux and/or chronic venous insufficiency. The award,...
Klox Technologies Inc. (Klox), a regenerative medicine company focused on the development of fluorescent light energy biomodulation systems for applications in dermatology and wound care, has announced that it has completed the acquisition of FB Dermatology, a specialized dermatology...
Caitlin Hicks (Baltimore, USA) talks to BLearning at SVS 2019 (Society for Vascular Surgery; 12–15 June; Washington DC, USA) about why it is so important to save limbs and the huge impact limb salvage can have on a patient’s...
Imbed Biosciences has announced that it has been awarded a US$1.5 million two-year Small Business Innovation Research (SBIR) grant from the National Institute for Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health (NIH). According...
 Julien Hasselmann (Malmö, Sweden) talks to iWounds News at ESVS 2019 (European Society of Vascular Surgery; 24–27 September; Hamburg, Germany) about the recent findings of the INVIPS trial which looked at the effect of negative pressure wound therapy (NPWT)...
Axxess is partnering with Swift Medical to provide thousands of home health agencies access to advanced wound care management. "Swift Medical's wound management capabilities complement what Axxess provides within our solution and enables us to deliver even more value to...
Huntleigh has announced the UK release of an innovative technology that is designed to assist in the management of hard-to-heal leg ulcers. Developed at the Arjo R&D Faculty in Cardiff, the Wound Express Advanced Wound Therapy Device is designed...
EO2 Concepts has announced the publication of a post hoc analysis from its randomised, double-blinded, multi-centre study, published last year in the Journal of Wound Care. This latest study evaluates the positive impact which continuous diffusion of oxygen (CDO), with...
LimFlow has announced that the US Food and Drug Administration (FDA) has approved its investigational device exemption (IDE) for the PROMISE II pivotal study of the LimFlow Percutaneous Deep Vein Arterialisation (pDVA) System. PROMISE II is a multicentre, prospective, single-arm study...
New data presented at the 2019 American Society of Colon and Rectal Surgeon’s Annual Scientific Meeting by Justin Malek, Baylor Scott & White Health, reveal that the CleanCision System, an advanced irrigating wound protection therapy, was shown to reduce...
The National Alliance of Wound Care and Ostomy (NAWCO) has announced the first professional credential to recognize clinical expertise in advanced wound care at the 2019 Wild On Wounds (WOW) national conference in Las Vegas, USA. According to a statement,...
MolecuLight Inc., a provider of handheld real-time fluorescence imaging for chronic wounds, has announced the publication of "Fluorescence imaging guided dressing change frequency during negative pressure wound therapy: a case series": a new paper published today in the Journal...
Cook Regentec has announced enrolment of the first patient in an international clinical trial evaluating the HemaTrate Blood Filtration System to treat patients with critical limb ischemia (CLI) due to peripheral arterial disease (PAD). To treat CLI, the HemaTrate...
Smith+Nephew has announced the US launch of its new PICO 7Y Single Use Negative Pressure Wound Therapy System (sNPWT) with AIRLOCK technology. This is the first PICO sNPWT pump to include an integrated Y connector, enabling the utilisation of...
Omar Ishrak, Medtronic’s chairman and CEO is to retire on 26 April 2020, following the end of the company’s current fiscal year. Also, the Medtronic Board of Directors has announced key leadership appointments as part of its multi-year, leadership...
Michael Edmonds, a pioneer in the treatment of the diabetic foot, has underlined the need for innovation and development in the wound care field. Today, the emergence of multiple randomised controlled trials (RCTs) is driving the effort to upgrade...
At the Charing Cross Symposium (15–18 April 2019, London, UK), Ian Chetter (Hull, UK) presented on the pathway from assessment to treatment for patients with surgical wounds healing by second intention (SWHSI), discussing the impact this may have on...
A study into the efficacy of early reflux elimination for venous leg ulcer (VLU) patients has revealed that the combination of ultrasound-guided foam sclerotherapy (UGFS) only, and a hybrid method of endovenous laser treatment (EVLT) with UGFS, could present...
MolecuLight Inc., a provider of handheld fluorescence imaging for real-time visualization of bacteria for chronic wounds, has announced it has secured a US$7.5 million term loan from Oxford Finance LLC, a specialty finance firm providing senior debt to life...
The impact of chronic wounds—a global “healthcare problem”—is felt by patients and the medical community, yet there is limited education on the management of wounds and no standard training programme currently in place. Karen Imma Gellada, a member of...
ZipLine Medical, Inc. has announced the publication of positive results from clinical studies in two peer-reviewed journals, demonstrating that the use of Zip Surgical Skin Closure leads to better clinical outcomes and healthcare cost savings than surgical staples. A randomised,...
Engineers at Heriot-Watt University, Edinburgh, UK, are developing a sensor that will help patients, doctors and nurses manage how wounds heal. Wounds cost the NHS between £4.5 and £5.1 billion each year to manage, while burns, diabetic ulcers, caesarean...
Results from two open prospective trials have revealed that the TLC-NOSF sucrose octasulphate dressing, with poly-absorbent fibres, represents an effective and safe treatment for the local management of leg ulcers. In addition, cost-effectiveness studies examining the economic impact of...
Members of the International Working Group on the Diabetic Foot (IWGDF) presented up-to-date guidelines for the diagnosis, prognosis and treatment of diabetic foot ulcers at the 29th conference of the European Wound Management Association (EWMA; 5–7 June, Gothenburg, Sweden),...
Two-year results from the MOBILE (Marrowstim treatment of limb ischaemia in patients with severe peripheral arterial disease) trial indicate that injecting concentrated bone marrow aspirate (cBMA, Zimmer Biomet), vs. placebo, into patients with critical limb ischaemia is associated with...
In her presentation at the Royal Society of Medicine Venous Forum (RSMVF; 17–19 June, London, UK), consultant vascular surgeon Emma Wilton (Oxford University Hospitals, Oxford, UK) outlined the important process for identifying which patients with leg ulceration require deep...
Endovenous laser ablation (EVLA) of perforating veins has been established as an effective method of treating chronic venous ulcers in patients with diabetes mellitus, according to a new study conducted in Azerbaijan. Results of the study, which involved 42 patients...
A member of the UK parliament has emphasised the need for a national wound care strategy during a recent debate in the House of Commons, highlighting that “diagnosis is difficult, but rapid diagnosis is absolutely essential”. Ann Clywd, MP...
Hoth Therapeutics, a biopharmaceutical company focused on targeted therapeutics for patients suffering from indications such as dermatological and chronic wound disorders, has announced the initial results of its pilot study on the application of the BioLexa Platform on diabetic...
 Karen Bauer (Toledo, USA) discusses the wound care limb salvage track at C3 which offered the “opportunity for clinicians from multiple disciplines to get together and talk about some really cutting-edge” topics. Bauer, a wound specialist, says that at the...
Rajesh Dave (Camp Hill, USA) talks to iWounds News about his highlights from the 15th annual C3 conference, which included a special session on the paclitaxel controversy. Dave talks about the “journey of 15 years” and how the meeting started...
An Expert Panel report published in The Diabetic Foot Journal has recommended a new treatment algorithm for topical oxygen therapy in patients with diabetic foot ulcers (DFUs) and called for it to be considered as an adjunct to standard of...
The TLC-NOSF (UrgoStart, Urgo Medical) advanced wound care dressing was recently recommended by the UK National Institute for Health and Care Excellence (NICE) for healing of venous and diabetic foot ulcers. Speaking at the European Wound Management Association annual...
Four years ago, vascular experts from around the world had a "quixotic quest", to get all surgeons and providers to agree on the best ways to treat a common and debilitating illness: chronic limb-threatening ischaemia. The goal has come...

Michael Edmonds

Michael Edmonds is professor of Diabetic Foot Medicine, King’s College London, and consultant physician, King’s College Hospital, London, UK. A pioneer in many areas of the diabetic foot, Edmonds speaks about his interest in diabetes and its treatment, the...
Preliminary findings from an initial study with 25 patients have shown that measuring the changes in oxygen concentration at baseline, during, and after endovascular revascularisation, can predict wound healing and functional improvement in critical limb ischaemia patients. Marianne Brodmann, Medical...
The opening of an outpatient wound centre has been associated with a significant increase in peripheral vascular practice and a significant decrease in amputation rate. Venita Chandra and colleagues Alyssa M Flores, Matthew W Mell and Ronald L Dalman...
The 2019 Charing Cross Symposium (CX; 15–18 April, London, UK) saw the introduction of a new strand of care with the debut of the iWounds Workshop to the exhibition hall. The iWounds Workshop aimed to promote early diagnosis of...
Keith Harding advocates for the increased involvement of medical staff in the treatment of patients with wound healing difficulties, as the number of chronic wounds seen in hospitals is on the rise. He argues that wounds “do not receive...
CX Executive Board member Una Adderley (Wakefield, UK), director of the National Wound Care Strategy Programme for the National Health Service (NHS) England, spoke recently at the 2019 Charing Cross Symposium (CX; 15–18 April, London, UK) on the challenge...
There is a robust evidence base to support the use of compression therapy for healing venous leg ulceration and for preventing ulcer recurrence. The most recent version of the Cochrane Review1 on the effectiveness of compression and the relative effectiveness of different...
Speaking at the Leipzig Interventional Course (LINC; 22–25 January, Leipzig, Germany), Katja Mühlberg of the University of Leipzig, Germany, called for an improvement in the evidence base around the role of compression in healing venous leg ulcers (VLU). Mühlberg...
The UK's National Institute of Health and Care Excellence (NICE) has published new guidance recommending UrgoStart wound dressings (Urgo Medical) for treatment of diabetic foot ulcers and venous leg ulcers. In a press release, Urgo Medical states that use...
Healogics, a provider of advanced chronic wound care services in the USA, has announced they have added vein ablation to their in-house service offerings through a new programme called Healogics VeinCare. This programme allows the company to provide patients...
Despite what current guidelines denote, and in addition to the emergence of data supporting the early intervention of venous ulceration, Alun Davies (London, UK) put forward that the recommendations are consistently being ignored, and highlighted that: “Urgent action is...
“A lot more bacteria than anticipated” have been discovered on wounds in a patient cohort consisting of 89% venous leg ulcers, and using fluorescence imaging proved superior for detecting infection in wounds. This was the conclusion of Tomas Serena (Warren,...
Defining success in venous ulcer healing, and for all chronic wounds, remains a nebulous concept—with no consensus on what constitutes a successful outcome. Dave Bosanquet (Bristol, UK) outlined the difficulties at the Charing Cross Symposium (CX; 15–18 April, London,...
 Michael Edmonds (London, UK), Thomas Serena (Warren, USA), Keith Harding (Cardiff, UK), and Williams Ennis (Oak Lawn, USA) talk at Charing Cross Live about the first ever iWounds workshop, the importance of wound management and what they hope to...
The UK National Institute for Health and Care Excellence (NICE) has released new recommendations for use of the PICO negative pressure wound dressing (Smith & Nephew) for closed surgical incisions, saying the negative pressure dressings are "associated with fewer...
InGeneron has announced the publication of results from an investigator initiated case series in chronic leg wounds in the Journal of the European Academy of Dermatology and Venereology. In the case series, InGeneron’s proprietary adipose-derived regenerative cell (ADRC) technology was...
William ennis illustration

William Ennis

Michael Edmonds